Resident Evil is a 2002 science fiction horror film based on the same titled series of survival horror games developed by Capcom. Borrowing elements from the video games Resident Evil and Resident Evil 2, the film follows an amnesiac heroine Alice, and a band of Umbrella Corporation commandos, as they attempt to escape a secret underground facility that at one time was filled with people but is now overrun with zombies. The film was directed by Paul W. S. Anderson. The film was commercially successful, grossing US$102,441,078 worldwide; however, it received many negative reviews from critics.
Although Resident Evil received negative reviews, financially it has been successful enough to have several #1 box office sequels made. Resident Evil was followed by three sequels: Resident Evil: Apocalypse (2004), Resident Evil: Extinction (2007) and Resident Evil: Afterlife (2010). Anderson continued his involvement in the series, writing and producing the sequels, however, leaving directing to Alexander Witt and Russell Mulcahy. Resident Evil stars Milla Jovovich, Michelle Rodriguez, Eric Mabius, and James Purefoy.
Inside The Hive, a top-secret genetic research facility owned by the Umbrella Corporation located deep beneath Raccoon City, a lab technician tosses away a blue vial in a lab, exits, and seals the room. The vial breaks and the facility’s security system, The Red Queen, detects possible infection, and in response, seals the Hive, killing everyone inside.
Elsewhere, Alice (Milla Jovovich) awakens in an empty mansion with amnesia. She and a police officer, Matt (Eric Mabius), are seized by a group of commandos and taken to an underground train station which leads to The Hive. They are joined by Spence (James Purefoy), who is also suffering from amnesia. The head of the commandos, “One”, explains that everyone in the group is an employee of the Umbrella Corporation. It is also revealed that The Red Queen is responsible for releasing a nerve gas in the mansion which has caused their amnesia. When the train arrives, the group opens and enters The Hive.
The group eventually finds their way to The Queen’s chamber; however, as they attempt to disable her, four of the commandos, including One, are killed. The only commandos left alive are Rain (Michelle Rodriguez), Kaplan, and J.D. Alice and Kaplan then shut The Queen down, opening the doors of the facility, releasing the now zombified staff and other experiments into The Hive. During a battle between the group and some of the zombies, Rain becomes infected after receiving multiple bite wounds.
As the group moves throughout The Hive, Alice and Spence slowly regain their memory. Later, Matt and Alice are separated and J.D. is killed while Kaplan, Rain, and Spence remain in near The Queen’s chamber. Still separated, Matt looks for information about his sister. Meanwhile, Alice encounters several dogs which were experimented on and surprises herself when she uses martial arts to defend herself.
Matt eventually finds his sister, Lisa, who is now a zombie. As she attacks him, Alice arrives in time to save him. Matt explains that he and Lisa unsuccessfully attempted to smuggle out a sample of the blue vial, the T-Virus, in the hopes of taking down Umbrella. Matt believes this to be the fault of Lisa’s contact, who supposedly betrayed her. Alice, remembering she was Lisa’s contact, remains silent.
Soon, the survivors are once more united at The Queen’s chamber and are forced to switch her back on to find an exit; The Red Queen agrees to help them. As Alice and the others try to escape through the maintenance tunnels, they are ambushed by zombies. Kaplan is separated from the rest of the team on their way to the train. Alice suddenly remembers that an anti-virus exists that could cure T-Virus infection.
Upon their arrival at the lab, they find that the vials containing the T-Virus and anti-virus are gone. Spence, fully regaining his memory, is shown as the sole person who released the virus and stashed the anti-virus near the train. He points a gun at the survivors then traps them in the lab. He then heads toward the train, but before he can inject himself with the anti-virus, he is killed by a mutated creature called the Licker.
Back at the lab, The Queen offers to spare Alice and Matt if they kill Rain, who has been infected for the longest period of time. As the Licker attempts to bash through the lab window to get to them, a sudden power-outage occurs. The laboratory door opens to reveal Kaplan, who has permanently disabled the Red Queen.
The four survivors start the train before The Hive is locked in quarantine. As the train heads back to the mansion, the Licker kills Kaplan and attacks the group. Alice battles the Licker as Matt kills a now zombified Rain. Matt, after having been clawed by the Licker, opens a trap door on the bottom of the train, causing the Licker to be dragged along the track and burned to death.
Matt and Alice arrive at the mansion, and escape at the last moment when the doors close. Suddenly, Matt begins to mutate as the two are seized by Umbrella scientists. The scientists announce that Matt is to be part of the “Nemesis Program”. Alice attempts to fend them off, but is ultimately subdued. The other scientists are then heard voicing their intentions to reopen The Hive.
Later, Alice awakens at the Raccoon City Hospital, locked in an observation room. After escaping the room and wandering the hospital’s empty halls, Alice exits the building to find Raccoon City abandoned with signs of chaos everywhere. Alice takes a shotgun from a nearby police car, as the destruction of the city is fully shown.